The Quantum-Safe 360 Alliance, including members Keyfactor, IBM Consulting, Thales, and Quantinuum, unveiled its first comprehensive guide to help organizations navigate the global transition to post-quantum cryptography (PQC). The white paper marks the formal debut of the Quantum-Safe 360 Alliance, an evolving collective of industry leaders with unparalleled expertise spanning cryptographic design and deployment, public key infrastructure (PKI) and certificate lifecycle management, crypto-agile development practices, and quantum-safe cryptography. Collaborating to help enterprises tackle the challenges of PQC transitions, the Alliance’s white paper signals a coordinated, public effort to provide clear guidance and accelerate preparedness for the quantum era. Drawing upon each Alliance member’s deep proficiency and diverse capabilities, the white paper highlights the urgency of quantum-safe preparedness and the risks of inaction and provides actionable guidance on building stronger crypto-agility and starting PQC transitions. Formed to promote a unified, cross-industry approach, the Alliance aims to provide coordinated expertise and interoperable solutions to help enterprises safeguard data in the quantum era. By pooling resources and knowledge, the Alliance aims to help enterprises navigate the quantum era, including supplying organizations with cybersecurity best practices and interoperable solutions designed to work cohesively across platforms and industries. Key topics the white paper addresses include: The necessity of cryptographic agility to adapt to evolving threats; The challenges enterprises face in securing internal buy-in for PQC and strategies to overcome them; Case studies highlighting the value of holistic post-quantum preparation guided by the expertise and skills of Alliance members; A strategic roadmap for enterprises to adopt cryptographic agility; and, Best practices and tools for implementing a quantum-safe infrastructure, including PKI management, key lifecycle strategies, and quantum-generated randomness for enhanced security.